Gunturodu movie is about Kanna (Manchu Manoj), a happy go lucky youth from Guntur who gets into a huge fight with a deadly criminal lawyer called Seshu (Sampath Raj). A very upset Seshu starts looking for Kanna and targets his father. On the other hand, Kanna falls in love with Seshu's only sister Amrutha (Pragya Jaiswal). Rest of the story is how Kanna manages to fight the mighty Seshu.