Lara, an intelligent college student, indulges in a fight with seniors and unintentionally commits a murder for which he gets jailed. His life takes a turn after meeting MLP at the prison and Lara turns into a small-time rowdy upon release. As Lara grows close to Poorna and opts to settle for a normal life, his past keeps haunting him. How Lara survives forms the crux of Rangu.

Sreemukhi (Priya Singh) decides to end her life after receiving a strange call. It is later learnt that it was a prank call by Arya (Manoj Nandan), who works for a TV channel. Arya and Sreemukhi turn out to be friends and decide to get married. After a series of events, misunderstandings arise between Arya and Sreemukhi. How they tackle the differences and unite forms the plot of Manasainodu.