'Rambo 5: Last Blood' is the last chapter of the heroic series. Rambo must confront his past and excavate his combat skills in order to seek revenge in one final mission. He has to travel to Mexico to save a friend's daughter who had been kidnapped by the Mexican Cartel.

When his housekeeper's daughter is kidnapped, John Rambo crosses the U.S.-Mexican border to battle against the ruthless Mexican cartels to bring her back home safely.