Puliraju, a happy go lucky youth wastes his time mostly in the company of women. Seeing this his father gets him married and forces him to have a baby boy. But asks his son to leave home and come back only with a male successor when he finds out that his daughter in law delivers a baby girl and cannot give birth to any more children. How Puliraju solves this issue forms the rest of the story.

Masti' is about five missing girls and the search to find them forms the rest of the story.