Nethra (Aishwarya Addala) doesn't believe in love and decides to marry a guy of her father's choice. Nethra often dreams of a man (Gopichand) who meets her after murdering a girl. One fine day, she meets the man of her wild dreams in real life and is startled by his existence. What happens next? A spooky story unfolds revealing a series of horrifying secrets.

Ee Cinema Superhit Guarantee is a tragic story of Nani (HM Mahadev) who always falls in love and end up with heartbreak. What is Nani's problem and why does he break up with everyone? The rest of the story forms the crux.